Disodium EDTA is a salt of ethylenediaminetetraacetic acid (commonly known as EDTA). In cosmetics, it functions primarily as a chelating agent, meaning it prevents ingredients in a formula from binding with trace elements (mainly minerals) that can be present in water or other ingredients.
Why is disodium EDTA used in cosmetics?
More Scientific Information: – EDTA (ethylenediamine tetraacetic acid) and its salts are substituted diamines. HEDTA (hydroxyethyl ethylenediamine triacetic acid) and Trisodium HEDTA are substituted amines. All of these ingredients function as chelating agents in cosmetics and personal care products.
What is the risk of disodium EDTA?
– Should you have any overexposure to the ingredient (more than 3g of disodium EDTA per day), take note of the side effects as follows, as noted in multiple studies.Too much of disodium EDTA can cause multiple side effects, including nausea, vomiting, diarrhea, low blood pressure, fever, and skin issues.
Disodium EDTA also found to cause interference with blood sugar management in diabetics as it can interact with insulin, affecting heart rhythm for anyone having irregular heart rhythm, and even making breathing tubes narrow due to nebulizers that are containing disodium EDTA as part of their ingredient, as well as issues with reproductive organs.
Since disodium EDTA is also working as a chelating agent, it can be dangerous when there’s an excess in the bloodstream as the ingredient can bind with potassium, increasing the concentration of the mineral to be flushed out through kidney. This, in turn, causes your body to have way low of the mineral, especially if you have it too low to begin with.
- A similar mechanism also applies to calcium and magnesium, causing your body to have the mineral too low, creating hypocalcemia (increasing the risk of getting seizures) and mineral imbalances worse.
- If you exceed than maximum limits, serious side effects include severe kidney damage, mineral imbalance in the bloodstream, and even death.
While disodium EDTA is deemed safe for use and consumption, we should be aware of the danger of overexposure and taking necessary steps to avoid getting one. After all, since the ingredient is pretty much everywhere, we need to be extra careful with products that we are using, slowly making our way to reduce the exposure to the ingredient to the bare minimum.
What is disodium EDTA made from?
Origin – Disodium EDTA is mainly synthesized from ethylenediamine (1,2-diaminoethane), formaldehyde, and sodium cyanide. This route yields the tetrasodium EDTA, which is converted in a subsequent step into the acid forms.
Is disodium EDTA good or bad for skin?
In several studies, the Cosmetics Review Board has found that as used in cosmetics products, disodium EDTA is safe. It was determined that in the concentrations used in commercial cosmetics, it is not a skin sensitizer nor a carcinogen, and does not penetrate through skin.
Why is EDTA harmful to skin?
Concerns – Known carcinogens are used to make tetrasodium EDTA—formaldehyde and sodium cyanide. Studies have shown the compound can make the skin’s protective barrier more fragile. This could cause other harmful chemicals to absorb into the skin and even other bodily systems.
Lab specimens have however not been found to develop cancer after exposure to tetrasodium EDTA. People with sensitive skin have, in rare cases, reported incidents of eczema development when using a product containing tetrasodium EDTA. When exposed to tetrasodium EDTA at high levels, lab specimens have developed skin irritations that could represent any risks posed to humans who use products with this ingredient.
When given to lab specimens orally, tetrasodium EDTA has caused negative reproductive and developmental reactions. Those with sensitive skin may react negatively to tetrasodium EDTA and may even display allergy symptoms such as irritation, rashes, and inflammation.
It is important to consult with a qualified physician about how to use products containing the compound or about alternative products to use for skincare needs. Dioxane, also a known carcinogen, is a by-product of the manufacturing process for tetrasodium EDTA. This ingredient does not degrade easily, raising environmental concerns.
Tetrasodium EDTA can irritate the eyes. The compound is labeled in some cosmetic products as TEA-EDTA, tetrasodium salt, edetate sodium, and tetrasodium edetate. https://www.advanced-dermatology.com.au/wp-content/uploads/2016/07/Tetrasodium-EDTA.jpg 413 377 Advanced Dermatology https://www.advanced-dermatology.com.au/wp-content/uploads/2018/03/Advanced-Dermatology-logo2.png Advanced Dermatology 2016-01-06 14:21:23 2016-07-04 14:26:42 Tetrasodium EDTA SculpSure Immortal Cream
Is EDTA harmful to the body?
Precautions – The most common side effect is a burning sensation at the site of the injection. In addition, some people may have an allergic reaction to EDTA. Other serious side effects that have been reported include low blood sugar, diminished calcium levels, headache, nausea, dangerously low blood pressure, kidney failure, organ damage, irregular heartbeat, seizures, or even death.
- According to the Centers for Disease Control and Prevention (CDC), there have been deaths associated with hypocalcemia (low levels of calcium) from intravenous chelation therapy.
- A qualified health care provider will monitor blood pressure, blood glucose, cholesterol, organ function, and other vital statistics during treatment with EDTA.
EDTA may lower levels of nutrients such as calcium, zinc, and potassium. Your provider will perform blood tests to monitor vitamin and mineral levels before, during, and after EDTA chelation therapy. Your doctor may recommend supplemental vitamins and minerals, either orally or intravenously.
Is EDTA natural or synthetic?
It is mostly synthesized from 1, 2-diaminoethane (ethylene diamine), formaldehyde, water and sodium cyanide. This yields the tetrasodium salt, which can be converted into the acidic forms by acidification. This review will address the different indications and considerations for EDTA.
Is disodium EDTA a preservative in cosmetics?
Disodium EDTA is in many products as a preservative, to stabilise it, or to enhance the foaming action.
Is disodium EDTA a preservative in cosmetics?
Disodium EDTA is in many products as a preservative, to stabilise it, or to enhance the foaming action.
What was the purpose of adding the EDTA?
Continuing Education Activity – Ethylenediaminetetraacetic acid (EDTA) is a medication used in the management and treatment of heavy metal toxicity. It is in the chelating class of drugs. This activity outlines and reviews the indications, actions, and contraindications for EDTA as a valuable agent in managing lead toxicity.
Outline the indications for EDTA. Identify the most common adverse effects associated with EDTA therapy. Explain the importance of monitoring for patients on EDTA therapy, including renal function tests. Identify the mechanism of action of EDTA.
Access free multiple choice questions on this topic.
What is the purpose of EDTA products?
Chelation therapy products, including EDTA, are agents that bind to heavy metals in the body, allowing them to pass through the body faster. Chelation therapy products are available via prescription. Prescription products are approved for conditions such as heavy metal toxicity and very high calcium levels.