What Is Pvp In Cosmetics?

What Is Pvp In Cosmetics
Synthetic. Polyvinylpyrrolidone (PVP) gives products an extra fixative power: it forms a thin coating over the hair that helps to maintain it in the position you wish. PVP promotes the dispersion of pigments, making it a very effective ingredient for creating well spread out makeup products.

Is PVP safe in cosmetics?

More safety Information: – CIR Safety Review: The CIR Expert Panel, in reviewing the available data, on PVP decided to include studies on the PVP-iodine complex. The CIR Expert Panel acknowledged that although the complex is a separate entity from the, the majority of studies conducted on the complex demonstrated its safety.

FDA: Link to Code of Federal Regulations for Polyvinylpyrrolidone (PVP)PVP may be used in cosmetics and personal care products marketed in Europe according to the,Link to the EU Cosmetic Regulation: The Joint FAO/WHO Expert Committee on Food Additives has established an Acceptable Daily Intake for PVP of 0-50 mg/kg body weight.

PVP is a linear of 1-vinyl-2-pyrrolidone monomers. PVP is soluble in water and other polar solvents. When dry, it is a light flaky powder, which readily absorbs up to 18% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films.

Is PVP in hair products safe?

Get hair, health, and science news delivered right to your inbox. – Medically Reviewed by You use hair care and styling products every day — but do you even know what’s actually in them? Take a look inside your bathroom cabinets and drawers. Chances are, you have a collection of hair products that are synthetically derived and filled with substances that can potentially harm your hair.

That’s because the United States isn’t the most aggressive country when it comes to banning harmful chemicals in hair products: Europe and Canada have banned hundreds of ingredients that are unfortunately still permitted in the US market.
This makes it especially important for American consumers to be aware of what ingredients are in their products.

Not sure what to look out for? The experts at Nutrafol came up with a list of you should avoid putting in your hair. If you see any of these listed as an ingredient on a hair product, think twice before purchasing: With its smoothing properties, mineral oil performs well as a detangler or hair conditioner.

But mineral oil contains significant levels of PAHs (polyaromatic hydrocarbons), potentially linking it to, Because cancer usually means some sort of dysregulated immune signaling — and immune signaling is crucial in a healthy cycling follicle — even a small amount of this ingredient could be harmful to hair cells.

Petroleum jelly comes from the same source as mineral oil and poses similar risks. This ingredient may be associated with an increased risk of cancer due to PAHs. PVP/VA copolymer is the ingredient found in most hair care products that provides the “hold factor.” (Think: hairsprays.) It is another toxic chemical derived from petroleum that’s known to cause irritation to the scalp, as well as respiratory issues in some people.

Is PVP a natural ingredient?

Written by EverEscents on December 17, 2013, Posted in Ingredients We Avoid, PVP/VA Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel’s, wax’s, pomades and styling creams.

It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair.

PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people.

Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Here at EverEscents we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray.

This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. To find out more about this product or any others, please head to www.everescents.com.au Sourced From: http://btruenaturals.com/index.php?app=cms&ns=display&ref=pvp http://thechalkboardmag.com/toxic-timeout-pvpva-copolymer EverEscents, hairspray, liquid plastic, natural, organic, Organic Hair Care, Organic Haircare, organic hairspray, PVP Copolymer, pvp/va copolymer

What is PVP material?

Abstract – Polyvinylpyrrolidone (PVP) is a water-soluble polymer obtained by polymerization of monomer N -vinylpyrrolidone. PVP is an inert, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs.

These advantages enable PVP a versatile excipient in the formulation development of broad conventional to novel controlled delivery systems.
PVP has tunable properties and can be used as a brace component for gene delivery, orthopedic implants, and tissue engineering applications.
Based on different molecular weights and modified forms, PVP can lead to exceptional beneficial features with varying chemical properties.

Graft copolymerization and other techniques assist PVP to conjugate with poorly soluble drugs that can inflate bioavailability and even introduces the desired swelling tract for their control or sustained release. The present review provides chemistry, mechanical, physicochemical properties, evaluation parameters, dewy preparation methods of PVP derivatives intended for designing conventional to controlled systems for drug, gene, and cosmetic delivery.

The past and growing interest in PVP establishes it as a promising polymer to enhance the trait and performance of current generation pharmaceutical dosage forms. Furthermore, the scrutiny explores existing patents, marketed products, new and futuristic approaches of PVP that have been identified and scope for future development, characterization, and its use.

The exploration spotlights the importance and role of PVP in the design of Povidone-iodine (PVP–I) and clinical trials to assess therapeutic efficacy against the COVID-19 in the current pandemic scenario. Keywords: Polyvinylpyrrolidone, Povidone-iodine, Polymer, Excipient, Drug delivery, Conventional dosage forms, Controlled release, COVID 19 Abbreviations: Polyvinylpyrrolidone, PVP

Is PVP a silicone?

The model above is an image of the pdb model you can view by clicking here or you can just click on the image itself. Either way, be sure to close the new window that opens up with the 3D model in it when you are ready to come back here. For polyvinylpyrrolidone at a glance, click here! Polyvinylpyrrolidone is found in a lot of places where you wouldn’t expect to find polymers.

What kind places? For example, polyvinylpyrrolidone was the main ingredient in the first really successful hairsprays in the early 1950s. That’s right, the eventual giant beehive hairdos that followed in the sixties owed their existence to polyvinylpyrrolidone. This polymer worked as a hairspray because it was soluble in water.

This meant it could be rinsed out when you wash your hair. But its affinity for water gave it a drawback. Polyvinylpyrrolidone tended to adsorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane.

To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Now remember, most of the time, two different kinds of polymers will not blend or mix together homogeneously.

So if we put some of the silicone in the hairspray, the silicone and the polyvinylpyrrolidone will phase separate once they’re on the hair. You can see what we get in this picture: The silicone forms a layer on top of the polyvinylpyrrolidone layer that keeps water out, so the hair has a more natural look. But that’s not all polyvinylpyrrolidone can do. Its found in the glue that holds plywood together. But if want a more exciting use than that, I’ll tell you that this polymer can actually save lives.

Sometime in the first half of the twentieth century, someone figured out that a patient who has lost a lot of blood can be given blood plasma, and the plasma will help keep the patient alive until whole blood can be administered. But sometimes even blood plasma is hard to find, and we have to figure out how to make the plasma go further.

One such time and place is on a battlefield. During the Second World War and the Korean War blood plasma was diluted with polyvinylpyrrolidone, so that more of the injured could be treated with the limited supplies of blood plasma. Of course the much simpler idea of just not having a war in the first place doesn’t seem to have occurred to anyone. This is what the monomer looks like in 3-D: The model above is an image of the pdb model you can view by clicking here or you can just click on the image itself. Either way, be sure to close the new window that opens up with the 3D model in it when you are ready to come back here.

Is PVP a Microplastic?

How to Read the Shampoo Ingredients List – Most of us will rarely scan an ingredient list of our cosmetic products, unless we are sensitive or allergic to something. In other instances, the long scientific names can make us zone out. Hopefully, we can inspire you to take an extra minute to study the list to better make sustainable decisions for your bathroom purchases.

Polyethylene (PE) Polyethylene terephthalate (PET) Nylon (PA) Polypropylene (PP) Polymethyl methacrylate (PMMA)

Alongside these common microbead ingredients, there are a lot of other nasties, such as resins, waxes and silicones that are formulated to cosmetically coat your hair shaft. They all promise to create beautiful, luxurious and hydrated hair full of volume and shine. Further synthetic ingredients in cosmetics – The Orange List*

Polyethilene Glycol (PEG), mostly found abbreviated with other numbers like PEG-4 or PEG-80 etc. Polypropylene glycols (PPG) Dimethicone Cyclomethicone Acrylates Copolymers Methylchloroisothiazolinone Methylisothiazolinone Paraffin Waxes

A part from the microplastics in shampoo, the plastic most commonly found in hair sprays is Polyvinylpyrrolidone (PVP). It is at its most dangerous point when applied to the hair and heated up with styling tools. This effectively melts the plastic for us to breath in and can cause damage to the lungs in sensitive individuals.

*For further information on microplastics and microbeads in cosmetics, please refer to the Guide to Microplastics on the “Beat the Microbead” website, a campaign by the Plastic Soup Foundation. Based on the restriction proposal by the European Chemical Agency (ECHA) and the reports by the United Nations Environmental Program, they came up with a list of more than 500 microplastic ingredients that are widely used in cosmetics & personal care products and split them according to the severity in which they affect the environment in a Red, Orange, Green or Zero microplastics list.

They even launched an app that you can use to scan the cosmetic products you’re using to see if they contain microbeads.

What does PVP do in skincare?

PVP, short for polyvinylpyrrolidone, is one of the primary ingredients used in hairstyling products to hold hair in place. When present in minuscule amounts in skin-care products, it places an imperceptible film over the skin that is considered to be water-binding and that helps give the appearance of firmer skin.

Is polyvinylpyrrolidone toxic?

4. Conclusions – According to the conceptual framework for the risk assessment of certain food additives re‐evaluated under Commission Regulation (EU) No 257/2010 (EFSA ANS Panel, 2014) and given that:

the exposure assessment carried out by the Panel was based on the reported use and use levels (one food category out of the two food categories in which PVP and PVPP are authorised);
the 95th percentile of exposure to PVP and PVPP of maximally 23.7 and 25 mg/kg bw per day in children, respectively, was overestimated, because it was assumed that 100% of the food supplements consumed contained PVP or PVPP at the maximum reported use levels;
extension of use of PVP (E 1201) to foods for special medical purposes (FC 13.2) would result in an exposure of PVP of 4.3 mg/kg bw per day for children;
the absorption of PVP and PVPP is very low;
sufficient toxicity data were available for PVP;
there is no concern with respect to the genotoxicity of PVP and PVPP;
no carcinogenic effects were reported in carcinogenicity studies in rats at a dose of 2,500 mg PVP/kg bw per day, the highest dose tested;
there is no need for chronic toxicity/carcinogenicity data for PVPP for the safety assessment of PVPP given the chemical similarity between PVP and PVPP, and the lack of adverse effects in the available repeated dose toxicity studies;

the Panel concluded that there is no need for numerical ADIs for PVP and PVPP, and that there is no safety concern for the reported uses and use levels of PVP and PVPP as food additives. The Panel further concluded that the proposed extension of use is not expected to be of safety concern at the proposed MPL and recommended consumption level.

What does PVP do to your hair?

Polyvinylpyrrolidone (PVP) gives products an extra fixative power: it forms a thin coating over the hair that helps to maintain it in the position you wish. PVP promotes the dispersion of pigments, making it a very effective ingredient for creating well spread out makeup products.

Is PVP Eco Friendly?

Share and Cite – MDPI and ACS Style Lu, S.; Li, C.; Liu, R.; Lv, A. PVP-Assisted Shellac Nanofiber Membrane as Highly Efficient, Eco-Friendly, Translucent Air Filter. Appl. Sci.2021, 11, 11094. https://doi.org/10.3390/app112311094 AMA Style Lu S, Li C, Liu R, Lv A.

PVP-Assisted Shellac Nanofiber Membrane as Highly Efficient, Eco-Friendly, Translucent Air Filter. Applied Sciences,2021; 11(23):11094. https://doi.org/10.3390/app112311094 Chicago/Turabian Style Lu, Shanshuai, Congling Li, Rui Liu, and Aifeng Lv.2021. “PVP-Assisted Shellac Nanofiber Membrane as Highly Efficient, Eco-Friendly, Translucent Air Filter” Applied Sciences 11, no.23: 11094.

https://doi.org/10.3390/app112311094 Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here,

What is alternative for PVP?

The technique of intracytoplasmic sperm injection (ICSI) requires mechanical immobilization of the sperm that are to be injected; damage thus caused to the sperm membrane is considered to be necessary to activate the sperm for fertilization. Mechanical immobilization and the injection procedure are facilitated by introducing the sperm into a viscous medium that will hinder motility: a solution of polyvinylpyrrolidone (PVP) has been used successfully for this purpose.

PVP is an artificial polymer, which has been regarded as chemically inert, although adverse effects have been reported as a result of its use both in vivo and in vitro,
Therefore, the use of hyaluronate, the natural component of the extracellular matrix of the cumulus-oocyte complex, was investigated as a replacement for PVP during ICSI.

A solution of hyaluronate was found to be as effective as PVP in facilitating the injection procedure, its effect on sperm motility was readily reversible, and its use did not affect the outcome of the treatment cycles in terms of fertilization, pregnancy and live birth rates.

Is PVPP plastic?

ibrew – Polyclar PVPP (granular) Polyclar (PVPP) is a finely ground (granular) — plastic material that works in relatively the same way as isinglass and gelatin with one important difference: it reacts more with the polyphenol part of the protein-polyphenol haze-forming complex so it does not seriously impede the foam quality of the beer.

Another interesting by-product of Polyclar’s fining action is that it can remove some oxidative browning; that is, it can lighten the color as well as clear the beer. Can be used in conjunction with whirfloc (irish moss) in which case it is added in the last stage of the boil. sold in 100gm vacuum sealed bags

: ibrew – Polyclar PVPP (granular)

Is PVP a powder?

1.4.11 Polyvinylpyrrolidone – Polyvinylpyrrolidone (PVP), commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N -vinylpyrrolidone, Dry PVP is a light flaky hygroscopic powder and readily absorbs up to 40% of water by its weight. Figure 1.20, Synthesis of polyvinylpyrrolidone. The PVP was used as a blood plasma expander for trauma victims. It is used as a binder in many pharmaceutical tablets and it simply passes through the body when it is administered orally, However, autopsies have found that crospovidone does contribute to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption,

PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.
This complex is used in various products like solutions, ointment, pessaries, liquid soaps, and surgical scrubs.
It is known under the trade name Betadine and Pyodine.
It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions).

For this purpose, povidone-iodine is equally effective and safe as talc and may be preferred because of easy availability and low cost, It is used as an aid for increasing the solubility of drugs in liquid and semiliquid dosage forms (syrups and soft gelatin capsules) and as an inhibitor of recrystallization.

How is polyvinylpyrrolidone produced?

Claims ( 10 ) – 1, A polyvinylpyrrolidone composition in a form of a solid preparation or an aqueous solution, the composition comprising polyvinylpyrrolidone, ammonia, and a secondary amine.2, The polyvinylpyrrolidone composition according to claim 1, wherein the secondary amine is selected from the group consisting of dialkanolamines and dialkylamines.3,

The polyvinylpyrrolidone composition according to claim 2, wherein the secondary amine is diethanolamine.4, A process for producing a polyvinylpyrrolidone composition according to claim 1, the process comprising heat drying a polyvinylpyrrolidone aqueous solution containing ammonia and a secondary amine to obtain the polyvinylpyrrolidone composition in a form of a solid preparation.5,

The process according to claim 4, wherein the polyvinylpyrrolidone aqueous solution is obtained by polymerizing N-vinyl-2-pyrrolidone using hydrogen peroxide as a polymerization initiator in a presence of a metal catalyst using ammonia and the secondary amine as promoters in an aqueous medium.6,

The process according to claim 4, wherein the polyvinylpyrrolidone aqueous solution is obtained by adding the secondary amine to an aqueous solution containing polyvinylpyrrolidone and ammonia.7, The process according to claim 6, wherein the aqueous solution containing polyvinylpyrrolidone and ammonia is obtained by polymerizing N-vinyl-2-pyrrolidone using hydrogen peroxide as a polymerization initiator in a presence of a metal catalyst using ammonia as a promoter in an aqueous medium.8,

A process for producing a polyvinylpyrrolidone composition according to claim 1, the process comprising adding a secondary amine to an aqueous solution containing polyvinylpyrrolidone and ammonia to obtain the polyvinylpyrrolidone composition in a form of an aqueous solution.9,

The process according to claim 8, wherein the aqueous solution containing polyvinylpyrrolidone and ammonia is obtained by polymerizing N-vinyl-2-pyrrolidone using hydrogen peroxide as a polymerization initiator in a presence of a metal catalyst using ammonia as a promoter in an aqueous medium.10,
A process for producing a polyvinylpyrrolidone composition according to claim 1, the process comprising polymerizing N-vinyl-2-pyrrrolidone using hydrogen peroxide as a polymerization initiator in a presence of a metal catalyst using ammonia as a promoter in an aqueous medium.

US11/377,422 2005-03-28 2006-03-17 Polyvinylpyrrolidone composition and processes for its production Abandoned US20060216263A1 ( en )

What is PVP in toothpaste?

Polyvinylpyrrolidone (PVP): Used to block tooth enamel from. developing stains. Sodium Bicarbonate (Baking Soda): Baking soda is commonly used as a mild abrasive to help remove tooth stains. Hydrated Silica: Also used as a mild abrasive to remove tooth stains.

Is PVP a hydrogel?

PVP is a biocompatible polymer with good chemical stability and solubility in water. Such hydrogel is often used in biomedical applications, such as contact lenses, wound dressings, drug delivery systems, or tissue engineering scaffolds, ].

Is PVP a resin?

Paint and Resin – Rahavard Tamin Pharmaceutical Co. Polyvinylpyrrolidone, RT.PVP®, (In paints and resins) RT.PVP features that make it quick to be used in a wide range of industries include:1) Solubility in water and more polar solvents2) ineffectiveness in terms of physiology and biocompatibility3) Lack of sensation and unpleasant skin sensation4) The ability to form a complex with other molecules5) The ability to form films6) Intrinsic adhesion7) Specific CondensationRT.PVP grades are presented in the form of white powder (or milky) and water-soluble in various molecular weights (Table 1).With the use of Dairy’s spray technology in the production of K30 powder, this grade is presented as a soft powder with excellent uniformity.

The K30 is rapidly dissolved in water due to its lower molecular mass, but the K90 grid with a high molecular mass is slowly dissolved in water and the final viscosity of the solutions at an equal concentration is greater than the K30 solutions.The adhesion strength of the K90 is greater than the K30.

This polymer can be used as an additive in all types of edible and non-edible products in soluble, suspension, gel and powder form. Table 1, RTPVP grading based on K-value.

Mw	K-value
10000	PVP K17
50000	PVP K30
400000	PVP K60
1000000	PVP K90

One of the common problems with emulsifying paint and emulsion coatings in water is poor dispersion, clotting or precipitation of pigments during storage. The use of PVP grades with low molecular mass (PVP K30) with the following functions leads to an increase in the quality of emulsion paints:1.

Improving the color of the product2. Stabilizing and maintaining the composition of the pigment content in the product3. Improved uniform coloringIn styrene-methyl acrylate emulsions, acrylic copolymer-based paints and, The viscosity of emulsion coating is often very low, resulting in poor resistance to water, making it difficult to control the thickness of the coating.In order to increase the viscosity, PVP grades with high molecular mass PVP K90 are also used to improve resin stability.

PVP-viscous emulsion coatings have a good rinse resistance and can aggravate the phenomenon of sagging and shading in the final coating.In addition, the addition of pvp to latex paints can increase the product’s thixotropic behavior. In fact, pvp, with many hydroxylated colloids such as starch, creates a picotropic color that, when applied to the surface, takes on a gel-like state.The 2-pyrrolidone product is also widely used as a green solvent and solvent in the manufacture of water-based inks.

An example of these formulations is as follows: Finally, the final color mix is added to the PVP solution to correct its rheological properties.

Thixotropic paint containing PVP part by weightPart 1. Butyl diethylene glycol acetate 9Sodium hexametaphosphate 1Sodium benzoate 2Sodium Carboxymethyl cellulose 6Sodium nitrite 2Water 166.5Part 2. Rutile TiO2 270Barytes 20Water 100Part 3. Copolymer latex(55% solid) “Vinyl acetate 75, butyl acrylate 15, 2-ethylhexyl acrylate 10″Starch ether(1% aqueous) and ammonium polymethacrylate (1% aqueous) (1:1)Part 4.

Is PVP a glue?

Sales Manager -Chlorhexidine, Povidone, 4-n-butylresorcinol,etc. – Published Nov 1, 2018 From the characteristics of polyvinylpyrrolidone PVP itself, PVP solid glue is a new type of environmentally solid glue, PVP (PVP = Polyvinylpyrrolidone, chemical name is polyvinylpyrrolidone, can also be written as PNVP, povidone, polyvidone, crospovidone, as a kind Water-soluble high molecular polymer, the monomer of which is N-Vinylpyrrolidone (N-vinyl-2-pyrrolidone), is a water-soluble polymer compound with excellent performance and wide application, and is a high-tech content and high value-added fine chemical product.

It is an important chemical intermediate and pharmaceutical intermediate advocated by the international government.
As a main material, it has a high viscosity, non-toxic and environmentally solid glue.
PVP solid glue features: high viscosity, suitable for office paper bonding; good slip, compared to PVA solid glue, the coating resistance is much smaller; safe and non-toxic, the production process does not have to add formaldehyde like PVA solid glue, at the same time PVP itself is a non-toxic original, so PVP solid glue is non-toxic and environmentally, especially suitable for children.

Polyvinylpyrrolidone PVP is not only a new environmentally material for solid glue, but also a green environmentally material for other colloids (pressure sensitive adhesive, rewet adhesive, adhesive)

Is PVP a thickener?

1 Kg PVP Thickener Product number: RMTH1KPVPK90 INCI Name: PVP Long-Name: Polyvinylpyrrolidone. Action: PVP has many functions including thickening, film forming and hair styling. It requires the presence of water to hydate the granules and as such is un-suitable for anhydrous formulations (water free, oil based).

Directions for use: Add to water phase and mix well using either a propellar mixer or homogeniser. Use Level: 0.1-5% Applications: * Can be used in mascarra to help adhere colour to the eyelash.* For sunscreens and active cosmetics where good skin adhesion is desirable.* For hair styling.* For Stabilising emulsions – this can be used as a water based thickener in the same way that xanthan gum or carbomer could be used.* Gelling agent in toothpaste.* Film former in gel or clay masks to help with drying and setting. Manufacturing Conditions: Heat and pH Stable.

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Does Vaseline contain microplastics?

MICROPLASTICS IN UNILEVER PRODUCTS – One of the absolute requirements of the ASN plastic policy is that companies may not use microplastics in cosmetics. It is a well-known problem that many personal care products contain added micro and nanoplastics.

The company says about this on the Unilever website: Unilever used to use small plastic scrub beads in a limited number of dedicated beauty & personal care products, such as exfoliating face and body washes. The plastic scrub beads were used as an ingredient because of their ability to gently remove dead skin cells from the surface of the skin.

Many consumers enjoy the clean feeling that using products with the beads provides. We stopped using plastic scrub beads in 2014. Unilever has banned exfoliating particles since 2014, but microplastics remain in many Unilever products, including products from the Dove, Vaseline, AXE, Lakmé, and Pond’s brands.

What does PVP do in skincare?

Is polyvinylpyrrolidone harmful to humans?

PVP has been shown to cause sarcomas in rats but there is not confirmation that it is carcinogenic in human patients. The material may cause irritation or dermatitis in some individuals upon prolonged contact.

Is polyvinylpyrrolidone safe to ingest?

the exposure assessment carried out by the Panel was based on the reported use and use levels (one food category out of the two food categories in which PVP and PVPP are authorised);
the 95th percentile of exposure to PVP and PVPP of maximally 23.7 and 25 mg/kg bw per day in children, respectively, was overestimated, because it was assumed that 100% of the food supplements consumed contained PVP or PVPP at the maximum reported use levels;
extension of use of PVP (E 1201) to foods for special medical purposes (FC 13.2) would result in an exposure of PVP of 4.3 mg/kg bw per day for children;
the absorption of PVP and PVPP is very low;
sufficient toxicity data were available for PVP;
there is no concern with respect to the genotoxicity of PVP and PVPP;
no carcinogenic effects were reported in carcinogenicity studies in rats at a dose of 2,500 mg PVP/kg bw per day, the highest dose tested;
there is no need for chronic toxicity/carcinogenicity data for PVPP for the safety assessment of PVPP given the chemical similarity between PVP and PVPP, and the lack of adverse effects in the available repeated dose toxicity studies;